基因試紙測肝癌 滴血代手術

基因試紙測肝癌 滴血代手術

2011-03-25
[align=center][img=380,252]http://simg.sina.com.hk/cp/0/0063/6734/2/p.jpg[/img][/align][align=center]中大醫學院兩名學者獲頒本年度裘槎基金會優秀科研者獎，左為專門研究肝病的陳力元，右為腦中風專家黃家星。（何家達攝）[/align]簡單如驗血糖  七成準【明報專訊】肝癌是香港第二號癌症殺手，潛伏期難以發現，中大內科及藥物治療學系教授陳力元發現，一些乙型肝炎患者的病毒基因，可能引致肝癌，但現時驗肝手術複雜，他研發出基因試紙，將來乙肝患者只需滴幾滴血，便可測試基因及預測肝癌爆發機會，準確率達七成。
裘槎基金會今年度向5名學者頒發「優秀科研者獎」，每人可獲80萬或90萬元讓所屬學校聘請代課教師，讓他們能休假專心研究，各得獎者亦獲研究補助金6萬元。
今年得獎者包括中大內科及藥物治療學系教授陳力元、中大腦神經科主任及何善衡心腦血管病中心主任黃家星、中大計算機科學與工程學系教授呂自成、科大生命科學部教授David Karl Banfield及城大數學系教授楊彤。
乙肝患者可測10年病發率肝臟專家陳力元透露，近年他研發的肝癌基因試紙，可預測乙肝患者在未來5至10年的肝癌病發機率。陳力元指出，本港約有50萬名乙肝患者，一些乙肝病毒基因已證實較有可能致癌，但驗肝需要用微創手術抽取肝纖維，遭病人抗拒，因而延誤診治。
陳力元近年和藥廠合作，08年初步發明肝癌基因試紙，但仍需樣本證明準確度，暫未能推出市場，他說：「將來任何人只需滴幾滴血，就如驗血糖般，在試紙上反映患肝癌的機率，評估未來數年發病情况，較容易被病人接受，又可節省醫院檢驗成本。」
中大app助家庭醫生評估此外，中大推出可評估肝癌風險的iPhone app，供醫生下載使用，醫生只要輸入臨牀測試數據，如年齡、血清膽紅素、血清白蛋白、肝硬化及乙型肝炎指數等，便可計算出患肝癌機率，方便家庭醫生在診所使用。
談到治療肝病的歷程，原來陳力元1996年正式加入威爾斯親王醫院是在腸胃科工作，他當年遇上一名20歲剛升大學的急性甲型肝炎患者急症入院，病人全身呈黃色，肝病更上腦，患者只能叫出自己名字，其父親更恐嚇陳力元：「你唔醫好我個仔，我打死你！」陳力元聽到感無奈，由於急性肝炎「無藥醫」，除了基本護理如抹身、轉身、放大便外，什麼也幫不上忙。自此，陳力元愛上與肝病這對手作戰。

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